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Purinergic P2 Receptor Agonists
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D058910 |
[Compounds that bind to and stimulate PURINERGIC P2 RECEPTORS.
] |
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Purinergic P2 Receptor Antagonists
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D058919 |
[Compounds that bind to and block the stimulation of PURINERGIC P2 RECEPTORS.
] |
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Purinergic P2X Receptor Agonists
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D058911 |
[Compounds that bind to and stimulate PURINERGIC P2X RECEPTORS. Included under this heading are agonists for specific P2X receptor subtypes.
] |
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Purinergic P2X Receptor Antagonists
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D058920 |
[Compounds that bind to and block the stimulation of PURINERGIC P2X RECEPTORS. Included under this heading are antagonists for specific P2X receptor subtypes.
] |
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Purinergic P2Y Receptor Agonists
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D058912 |
[Compounds that bind to and stimulate PURINERGIC P2Y RECEPTORS. Included under this heading are agonists for specific P2Y receptor subtypes.
] |
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Purinergic P2Y Receptor Antagonists
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D058921 |
[Compounds that bind to and block the stimulation of PURINERGIC P2Y RECEPTORS. Included under this heading are antagonists for specific P2Y receptor subtypes.
] |
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Purines
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D011687 |
[A series of heterocyclic compounds that are variously substituted in nature and are known also as purine bases. They include ADENINE and GUANINE, constituents of nucleic acids, as well as many alkaloids such as CAFFEINE and THEOPHYLLINE. Uric acid is the metabolic end product of purine metabolism.
] |
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Purinones
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D011688 |
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Purkinje Cells
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D011689 |
[The output neurons of the cerebellar cortex.
] |
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Purkinje Fibers
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D011690 |
[Modified cardiac muscle fibers composing the terminal portion of the heart conduction system.
] |
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Puromycin
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D011691 |
[A cinnamamido ADENOSINE found in STREPTOMYCES alboniger. It inhibits protein synthesis by binding to RNA. It is an antineoplastic and antitrypanosomal agent and is used in research as an inhibitor of protein synthesis.
] |
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Puromycin Aminonucleoside
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D011692 |
[PUROMYCIN derivative that lacks the methoxyphenylalanyl group on the amine of the sugar ring. It is an antibiotic with antineoplastic properties and can cause nephrosis.
] |
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Purple Membrane
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D018717 |
[Functionally and structurally differentiated, purple-pigmented regions of the cytoplasmic membrane of some strains of Halobacterium halobium. The membrane develops under anaerobic conditions and is made almost entirely of the purple pigment BACTERIORHODOPSINS. (From Singleton & Sainsbury Dictionary of Microbiology and Molecular Biology, 2d ed)
] |
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Purpura
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D011693 |
[Pinhead size (3 mm) skin discolorization due to hemorrhage.
, Purplish or brownish red discoloration, easily visible through the epidermis, caused by hemorrhage into the tissues. When the size of the discolorization is >2-3 cm it is generally called Ecchymoses (ECCHYMOSIS).
] |
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Purpura Fulminans
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D055665 |
[A severe, rapidly fatal reaction occurring most commonly in children following an infectious illness. It is characterized by large, rapidly spreading skin hemorrhages, fever, or shock. Purpura fulminans often accompanies or is triggered by DISSEMINATED INTRAVASCULAR COAGULATION.
] |
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Purpura, Hyperglobulinemic
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D011694 |
[Purplish or brownish red discoloration of the skin associated with increase in circulating polyclonal globulins, usually GAMMA-GLOBULINS. This syndrome often occurs on the legs of women aged 20 to 40 years.
] |
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Purpura, Schoenlein-Henoch
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D011695 |
[A systemic non-thrombocytopenic purpura caused by HYPERSENSITIVITY VASCULITIS and deposition of IGA-containing IMMUNE COMPLEXES within the blood vessels throughout the body, including those in the kidney (KIDNEY GLOMERULUS). Clinical symptoms include URTICARIA; ERYTHEMA; ARTHRITIS; GASTROINTESTINAL HEMORRHAGE; and renal involvement. Most cases are seen in children after acute upper respiratory infections.
] |
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Purpura, Thrombocytopenic
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D011696 |
[Any form of purpura in which the PLATELET COUNT is decreased. Many forms are thought to be caused by immunological mechanisms.
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Purpura, Thrombocytopenic, Idiopathic
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D016553 |
[Thrombocytopenia occurring in the absence of toxic exposure or a disease associated with decreased platelets. It is mediated by immune mechanisms, in most cases IMMUNOGLOBULIN G autoantibodies which attach to platelets and subsequently undergo destruction by macrophages. The disease is seen in acute (affecting children) and chronic (adult) forms.
] |
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Purpura, Thrombotic Thrombocytopenic
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D011697 |
[An acquired, congenital, or familial disorder caused by PLATELET AGGREGATION with THROMBOSIS in terminal arterioles and capillaries. Clinical features include THROMBOCYTOPENIA; HEMOLYTIC ANEMIA; AZOTEMIA; FEVER; and thrombotic microangiopathy. The classical form also includes neurological symptoms and end-organ damage, such as RENAL FAILURE. Mutations in the ADAMTS13 PROTEIN gene have been identified in familial cases.
] |
