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Proto-Oncogene Proteins p21(ras)
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D016283 |
[Cellular proteins encoded by the H-ras, K-ras and N-ras genes. The proteins have GTPase activity and are involved in signal transduction as monomeric GTP-binding proteins. Elevated levels of p21 c-ras have been associated with neoplasia. This enzyme was formerly listed as EC 3.6.1.47.
] |
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Proto-Oncogene Proteins pp60(c-src)
|
D016392 |
[Membrane-associated tyrosine-specific kinases encoded by the c-src genes. They have an important role in cellular growth control. Truncation of carboxy-terminal residues in pp60(c-src) leads to PP60(V-SRC) which has the ability to transform cells. This kinase pp60 c-src should not be confused with csk, also known as c-src kinase.
] |
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Proto-Oncogenes
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D011519 |
[Normal cellular genes homologous to viral oncogenes. The products of proto-oncogenes are important regulators of biological processes and appear to be involved in the events that serve to maintain the ordered procession through the cell cycle. Proto-oncogenes have names of the form c-onc.
] |
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Protocatechuate-3,4-Dioxygenase
|
D011520 |
[An enzyme that catalyzes the oxidation of protocatechuate to 3-carboxy-cis-cis-muconate in the presence of molecular oxygen. It contains ferric ion. EC 1.13.11.3.
] |
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Protochlorophyllide
|
D011521 |
[A photo-active pigment localized in prolamellar bodies occurring within the proplastids of dark-grown bean leaves. In the process of photoconversion, the highly fluorescent protochlorophyllide is converted to chlorophyll.
] |
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Proton Ionophores
|
D061209 |
[Chemical agents that increase the permeability of CELL MEMBRANES to PROTONS.
] |
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Proton Magnetic Resonance Spectroscopy
|
D066244 |
[Spectroscopy technique which measures changes in organic compounds by tracking the spectral energy of absorption of HYDROGEN atoms.
] |
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Proton Pump Inhibitors
|
D054328 |
[Compounds that inhibit H(+)-K(+)-EXCHANGING ATPASE. They are used as ANTI-ULCER AGENTS and sometimes in place of HISTAMINE H2 ANTAGONISTS for GASTROESOPHAGEAL REFLUX.
] |
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Proton Pumps
|
D017494 |
[Integral membrane proteins that transport protons across a membrane. This transport can be linked to the hydrolysis of ADENOSINE TRIPHOSPHATE. What is referred to as proton pump inhibitors frequently is about POTASSIUM HYDROGEN ATPASE.
] |
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Proton Therapy
|
D061766 |
[The use of an external beam of PROTONS as radiotherapy.
] |
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Proton-Coupled Folate Transporter
|
D058979 |
[A symporter protein that couples the transport of FOLIC ACID with HYDROGEN IONS. The transporter functions most effectively under acidic conditions.
] |
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Proton-Motive Force
|
D018892 |
[Change in HYDROGEN-ION CONCENTRATION across a membrane. The pH gradient together with the voltage gradient constitute an electrochemical proton gradient which exerts the PROTON-MOTIVE FORCE.
, Energy that is generated by the transfer of protons or electrons across an energy-transducing membrane and that can be used for chemical, osmotic, or mechanical work. Proton-motive force can be generated by a variety of phenomena including the operation of an electron transport chain, illumination of a PURPLE MEMBRANE, and the hydrolysis of ATP by a proton ATPase. (From Singleton & Sainsbury, Dictionary of Microbiology and Molecular Biology, 2d ed, p171)
] |
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Proton-Phosphate Symporters
|
D028081 |
[Proteins that cotransport hydrogen ions and phosphate ions across cellular membranes.
] |
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Proton-Translocating ATPases
|
D006180 |
[The transmembrane region of proton-translocating ATPase complexes. It contains three subunits named a, b and c.
, The catalytic sector of proton-translocating ATPase complexes. It contains five subunits named alpha, beta, gamma, delta and eta.
, Multisubunit enzymes that reversibly synthesize ADENOSINE TRIPHOSPHATE. They are coupled to the transport of protons across a membrane.
] |
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Protons
|
D011522 |
[Stable elementary particles having the smallest known positive charge, found in the nuclei of all elements. The proton mass is less than that of a neutron. A proton is the nucleus of the light hydrogen atom, i.e., the hydrogen ion.
] |
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Protoplasts
|
D011523 |
[The protoplasm and plasma membrane of plant, fungal, bacterial or archaeon cells without the CELL WALL.
] |
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Protoporphyria, Erythropoietic
|
D046351 |
[An autosomal dominant porphyria that is due to a deficiency of FERROCHELATASE (heme synthetase) in both the LIVER and the BONE MARROW, the last enzyme in the 8-enzyme biosynthetic pathway of HEME. Clinical features include mainly neurological symptoms, rarely cutaneous lesions, and elevated levels of protoporphyrin and COPROPORPHYRINS in the feces.
] |
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Protoporphyrinogen Oxidase
|
D050768 |
[A membrane-bound flavoenzyme that catalyzes the oxygen-dependent aromatization of protoporphyrinogen IX (Protogen) to protoporphyrin IX (Proto IX). It is the last enzyme of the common branch of the HEME and CHLOROPHYLL pathways in plants, and is the molecular target of diphenyl ether-type herbicides. VARIEGATE PORPHYRIA is an autosomal dominant disorder associated with deficiency of protoporphyrinogen oxidase.
] |
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Protoporphyrins
|
D011524 |
[Porphyrins with four methyl, two vinyl, and two propionic acid side chains attached to the pyrrole rings. Protoporphyrin IX occurs in hemoglobin, myoglobin, and most of the cytochromes.
] |
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Prototheca
|
D011525 |
[A genus of achlorophyllic algae in the family Chlorellaceae, and closely related to CHLORELLA. It is found in decayed matter; WATER; SEWAGE; and SOIL; and produces cutaneous and disseminated infections in various VERTEBRATES including humans.
] |
