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Pentaerythritol Tetranitrate
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D010417 |
[A vasodilator with general properties similar to NITROGLYCERIN but with a more prolonged duration of action. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1025)
] |
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Pentagastrin
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D010418 |
[A synthetic pentapeptide that has effects like gastrin when given parenterally. It stimulates the secretion of gastric acid, pepsin, and intrinsic factor, and has been used as a diagnostic aid.
] |
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Pentalogy of Cantrell
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D058502 |
[Rare congenital deformity syndrome characterized by a combination of five anomalies as a result of neural tube defect. The five anomalies are a midline supraumbilical abdominal wall defect (e.g., OMPHALOCELE), a lower STERNUM defect, a congenital intracardiac defect, an anterior DIAPHRAGM defect, and a diaphragmatic PERICARDIUM defect (e.g., PERICARDIAL EFFUSION). Variants with incomplete and variable combinations of the defects are known. ECTOPIA CORDIS; CLEFT LIP; and CLEFT PALATE are often associated with the syndrome.
] |
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Pentamidine
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D010419 |
[Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of PNEUMOCYSTIS pneumonia in HIV-infected patients. It may cause diabetes mellitus, central nervous system damage, and other toxic effects.
] |
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Pentanes
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D010420 |
[Five-carbon saturated hydrocarbon group of the methane series. Include isomers and derivatives.
] |
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Pentanoic Acids
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D010421 |
[Straight-chain CARBOXYLIC ACIDS with the general formula C5H10O2.
] |
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Pentanols
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D000439 |
[Isomeric forms and derivatives of pentanol (C5H11OH).
] |
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Pentanones
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D010422 |
[5-carbon straight-chain or branched-chain ketones.
] |
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Pentastomida
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D057078 |
[A subclass of CRUSTACEA comprising the tongue worms which are obligatory parasites of reptiles, birds, and mammals including humans.
] |
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Pentazocine
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D010423 |
[The first mixed agonist-antagonist analgesic to be marketed. It is an agonist at the kappa and sigma opioid receptors and has a weak antagonist action at the mu receptor. (From AMA Drug Evaluations Annual, 1991, p97)
] |
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Pentetic Acid
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D004369 |
[An iron chelating agent with properties like EDETIC ACID. DTPA has also been used as a chelator for other metals, such as plutonium.
] |
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Pentobarbital
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D010424 |
[A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)
] |
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Pentolinium Tartrate
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D010425 |
[A nicotinic antagonist that has been used as a ganglionic blocking agent in hypertension.
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Pentosan Sulfuric Polyester
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D010426 |
[A sulfated pentosyl polysaccharide with heparin-like properties.
] |
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Pentose Phosphate Pathway
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D010427 |
[An oxidative decarboxylation process that converts GLUCOSE-6-PHOSPHATE to D-ribose-5-phosphate via 6-phosphogluconate. The pentose product is used in the biosynthesis of NUCLEIC ACIDS. The generated energy is stored in the form of NADPH. This pathway is prominent in tissues which are active in the synthesis of FATTY ACIDS and STEROIDS.
] |
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Pentosephosphates
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D010428 |
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Pentoses
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D010429 |
[Monosaccharide sugar molecules that contain a five carbon backbone.
] |
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Pentostatin
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D015649 |
[A potent inhibitor of ADENOSINE DEAMINASE. The drug induces APOPTOSIS of LYMPHOCYTES, and is used in the treatment of many lymphoproliferative malignancies, particularly HAIRY CELL LEUKEMIA. It is also synergistic with some other antineoplastic agents and has immunosuppressive activity.
] |
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Pentosyltransferases
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D010430 |
[Enzymes of the transferase class that catalyze the transfer of a pentose group from one compound to another.
] |
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Pentoxifylline
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D010431 |
[A METHYLXANTHINE derivative that inhibits phosphodiesterase and affects blood rheology. It improves blood flow by increasing erythrocyte and leukocyte flexibility. It also inhibits platelet aggregation. Pentoxifylline modulates immunologic activity by stimulating cytokine production.
] |