|
Pemetrexed
|
D000068437 |
[A guanine-derived ANTINEOPLASTIC AGENT that functions as a NUCLEIC ACID SYNTHESIS INHIBITOR through its binding to, and inhibition of, THYMIDYLATE SYNTHASE.
] |
|
Pemoline
|
D010389 |
[A central nervous system stimulant used in fatigue and depressive states and to treat hyperkinetic disorders in children.
] |
|
Pemphigoid Gestationis
|
D006559 |
[An itching, autoimmune, bullous SKIN disease that occurs during the last two trimesters of PREGNANCY and PUERPERIUM. It also affects non-pregnant females with tissue of PLACENTA origin, such as CHORIOCARCINOMA; or HYDATIDIFORM MOLE. It exhibits antigenic and clinical similarity to bullous pemphigoid (PEMPHIGOID, BULLOUS). This disease does not involve herpes viruses (old name, herpes gestationis).
] |
|
Pemphigoid, Benign Mucous Membrane
|
D010390 |
[A chronic blistering disease with predilection for mucous membranes and less frequently the skin, and with a tendency to scarring. It is sometimes called ocular pemphigoid because of conjunctival mucous membrane involvement.
] |
|
Pemphigoid, Bullous
|
D010391 |
[A chronic and relatively benign subepidermal blistering disease usually of the elderly and without histopathologic acantholysis.
] |
|
Pemphigus
|
D010392 |
[Group of chronic blistering diseases characterized histologically by ACANTHOLYSIS and blister formation within the EPIDERMIS.
] |
|
Pemphigus, Benign Familial
|
D016506 |
[An autosomal dominantly inherited skin disorder characterized by recurrent eruptions of vesicles and BULLAE mainly on the neck, axillae, and groin. Mutations in the ATP2C1 gene (encoding the secretory pathway Ca2++/Mn2++ ATPase 1 (SPCA1)) cause this disease. It is clinically and histologically similar to DARIER DISEASE - both have abnormal, unstable DESMOSOMES between KERATINOCYTES and defective CALCIUM-TRANSPORTING ATPASES. It is unrelated to PEMPHIGUS VULGARIS though it closely resembles that disease.
] |
|
Pempidine
|
D010393 |
[A nicotinic antagonist most commonly used as an experimental tool. It has been used as a ganglionic blocker in the treatment of hypertension but has largely been supplanted for that purpose by more specific drugs.
] |
|
Penaeidae
|
D033561 |
[A family of CRUSTACEA, order DECAPODA, comprising the penaeid shrimp. Species of the genus Penaeus are the most important commercial shrimp throughout the world.
] |
|
Penbutolol
|
D010394 |
[A nonselective beta-blocker used as an antihypertensive and an antianginal agent.
] |
|
Penetrance
|
D019683 |
[The percent frequency with which a dominant or homozygous recessive gene or gene combination manifests itself in the phenotype of the carriers. (From Glossary of Genetics, 5th ed)
] |
|
Penfluridol
|
D010395 |
[One of the long-acting ANTIPSYCHOTIC AGENTS used for maintenance or long-term therapy of SCHIZOPHRENIA and other PSYCHOTIC DISORDERS.
] |
|
Penicillamine
|
D010396 |
[3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
] |
|
Penicillanic Acid
|
D010397 |
[A building block of penicillin, devoid of significant antibacterial activity. (From Merck Index, 11th ed)
] |
|
Penicillic Acid
|
D010398 |
[A mycotoxin with antibiotic and carcinogenic activity produced by various strains of PENICILLIUM and ASPERGILLUS. It has been found in tobacco, sausages, and corn.
] |
|
Penicillin Amidase
|
D010399 |
[An enzyme catalyzing the hydrolysis of penicillin to penicin and a carboxylic acid anion. EC 3.5.1.11.
] |
|
Penicillin G
|
D010400 |
[A penicillin derivative commonly used in the form of its sodium or potassium salts in the treatment of a variety of infections. It is effective against most gram-positive bacteria and against gram-negative cocci. It has also been used as an experimental convulsant because of its actions on GAMMA-AMINOBUTYRIC ACID mediated synaptic transmission.
] |
|
Penicillin G Benzathine
|
D010401 |
[Semisynthetic antibiotic prepared by combining the sodium salt of penicillin G with N,N'-dibenzylethylenediamine.
] |
|
Penicillin G Procaine
|
D010402 |
[Semisynthetic antibiotic prepared by combining penicillin G with PROCAINE.
] |
|
Penicillin Resistance
|
D010403 |
[Nonsusceptibility of an organism to the action of penicillins.
] |
