A reverse transcriptase encoded by the POL GENE of HIV. It is a heterodimer of 66 kDa and 51 kDa subunits that are derived from a common precursor protein. The heterodimer also includes an RNAse H activity (RIBONUCLEASE H, HUMAN IMMUNODEFICIENCY VIRUS) that plays an essential role the viral replication process.

Synonyms: EC 2.7.7.49, Reverse Transcriptase, Human Immunodeficiency Virus, HIV Reverse Transcriptase, Transcriptase, HIV Reverse, Reverse Transcriptase, HIV