A secreted matrix metalloproteinase that plays a physiological role in the degradation of extracellular matrix found in skeletal tissues. It is synthesized as an inactive precursor that is activated by the proteolytic cleavage of its N-terminal propeptide.

Synonyms: MMP-13 Metalloproteinase, MMP13 Metalloproteinase, Metalloproteinase, MMP13, Metalloproteinase 13, Matrix, MMP 13 Metalloproteinase, EC 3.4.24.-, Collagenase-3, Metalloproteinase, MMP-13, Matrix Metalloproteinase-13, Collagenase 3, Metalloproteinase-13, Matrix, Matrix Metalloproteinase 13