An E3 UBIQUITIN LIGASE that interacts with and inhibits TUMOR SUPPRESSOR PROTEIN P53. Its ability to ubiquitinate p53 is regulated by TUMOR SUPPRESSOR PROTEIN P14ARF.
Synonyms: c-mdm2, Proto-Oncogene Proteins, Mdm2 Protein, Mdm 2 Protein, Double Minute 2 Protein, EC 2.3.2.27, Murine Double Minute 2 Protein, Proto-Oncogene Proteins c-mdm2, Proto-Oncogene Protein, c-mdm2, c mdm2 Proto Oncogene Protein, Mdm-2 Protein, c-mdm2 Proto-Oncogene Protein, MDMX Protein, Proto Oncogene Proteins c mdm2
Instance information
comment
2006; PROTO-ONCOGENE PROTEINS C-MDM2 was indexed under PROTO-ONCOGENE PROTEINS 2005, & under NUCLEAR PROTEINS 1991-2005, & under NEOPLASM PROTEINS 1991-2004 ,2006(1991)
identifier
D051736