A fibroblast growth factor receptor which contains three extracellular IMMUNOGLOBULIN I-SET DOMAINS and is expressed as two isoforms. One receptor isoform is expressed in the MESENCHYME and is activated by FIBROBLAST GROWTH FACTOR 2. A second isoform is expressed mainly by EPITHELIAL CELLS and is activated by FIBROBLAST GROWTH FACTOR 7 and FIBROBLAST GROWTH FACTOR 10. Mutation of the gene for fibroblast growth factor receptor 2 can result in craniosynostotic syndromes (e.g., APERT SYNDROME; and CROUZON SYNDROME).
An isoform of fibroblast growth factor receptor 2 found mainly in EPITHELIAL CELLS that is activated by FIBROBLAST GROWTH FACTOR 7 and FIBROBLAST GROWTH FACTOR 10.
Synonyms: FGFR2b, FGFR2c, Receptor, Fibroblast Growth Factor, Type 2, Fibroblast Growth Factor Receptors 2, Bek-Related Fibroblast Growth Factor-Receptor-1, BEK Protein Tyrosine Kinase, EC 2.7.10.1, Fibroblast Growth Factor Receptors 2b, Bek Fgf Receptor Kinase, FGFR2 Protein, CD332 Antigen, BEK Fibroblast Growth Factor Receptor, Fibroblast Growth Factor Receptor 2, Fibroblast Growth Factor Receptor 2c, Fibroblast Growth Factor Receptor 2b, Receptor, Fibroblast Growth Factor 2c, Bek Related Fibroblast Growth Factor Receptor 1, Receptor, Fibroblast Growth Factor 2b, BEK Fibroblast Growth Factor Receptor Kinase, Antigen, CD332
Instance information
2006(1999) ,2006; FIBROBLAST GROWTH FACTOR RECEPTOR 2 was indexed under RECEPTORS, FIBROBLAST GROWTH FACTOR & RECEPTOR PROTEIN-TYROSINE KINASE 2004-2005, & under PROTEIN-TYROSINE KINASE 1999-2003
D051497