Steroidal compounds related to ESTRADIOL, the major mammalian female sex hormone. Estradiol congeners include important estradiol precursors in the biosynthetic pathways, metabolites, derivatives, and synthetic steroids with estrogenic activities.

Compounds obtained by chemical synthesis which possess estrogenic activity, but differ in structure from naturally occurring estrogens.

Synonyms: Congener, Estradiol, Analogue, Estrogen, Analogs, Estrogen, Estrogen Analog, Estrogens, Synthetic, Estrogen, Synthetic, Synthetic Estrogens, Estradiol Congener, Synthetic Estrogen, Estrogen Analogues, Estrogen Analogs, 0, Analogues, Estrogen, Analog, Estrogen, Estrogen Analogue, Estradiol Congeners