A vascular anomaly composed of a collection of large, thin walled tortuous VEINS that can occur in any part of the central nervous system but lack intervening nervous tissue. Familial occurrence is common and has been associated with a number of genes mapped to 7q, 7p and 3q. Clinical features include SEIZURES; HEADACHE; STROKE; and progressive neurological deficit.

Synonyms: Capillary Malformation, Cerebral, Cavernous Angiomatous Malformation, Angiomatous Malformations, Cavernous, Brain Cavernous Hemangiomas, Cerebral Capillary Malformations, Malformations, Cerebral Cavernous, Cavernous Hemangiomas, Intracerebral, Familial Cavernous Angioma, Intracerebral Cavernous Hemangiomas, Familial Cavernous Malformation, Cavernous Angioma, Central Nervous System, Malformation, Familial Cavernous, Hemangiomas, Cerebral Cavernous, Hemangiomas, Extracerebral Cavernous, Malformations, Cavernous Angiomatous, Cavernous Malformations, Familial, Malformations, Cerebral Capillary, Cavernous Hemangioma, Extracerebral, Cavernous Hemangioma, Central Nervous System, Cerebral Cavernous Malformations, Malformations, Familial Cavernous, Cavernous Malformation, Cerebral, Cavernous Hemangioma, Cerebral, Capillary Malformations, Cerebral, Cerebral Cavernous Hemangiomas, Cavernous Hemangiomas, Extracerebral, Central Nervous System Cavernous Hemangioma, Familial Cavernous Malformations, Malformation, Cerebral Capillary, Cavernous Angioma, Familial, Hemangioma, Cerebral Cavernous, Cavernous Angiomatous Malformations, Cavernous Hemangiomas, Cerebral, Intracerebral Cavernous Hemangioma, Cavernous Hemangioma of Brain, Cavernous Malformations, Cerebral, Malformation, Cavernous Angiomatous, Hemangioma, Intracerebral Cavernous, Cavernous Angiomas, Familial, Cerebral Cavernous Hemangioma, Extracerebral Cavernous Hemangiomas, Cavernous Malformation, Familial, Familial Cavernous Angiomas, Cerebral Cavernous Malformation, Cavernous Hemangioma, Intracerebral, Hemangiomas, Intracerebral Cavernous, Extracerebral Cavernous Hemangioma, Hemangioma, Cavernous, Central Nervous System, Hemangioma, Extracerebral Cavernous, Angiomatous Malformation, Cavernous, Angioma, Familial Cavernous, Malformation, Cerebral Cavernous, Angiomas, Familial Cavernous, Brain Cavernous Hemangioma, Cerebral Capillary Malformation