Proteins that regulate the signaling activity of GTP-BINDING PROTEINS. They are divided into three categories depending upon whether they stimulate GTPase activity (GTPASE-ACTIVATING PROTEINS), inhibit release of GDP; (GUANINE NUCLEOTIDE DISSOCIATION INHIBITORS); or exchange GTP for GDP; (GUANINE NUCLEOTIDE EXCHANGE FACTORS).

Synonyms: G Protein Regulating Factors, Regulators, G Protein Signaling, Regulating Factors, GTP-Binding Protein, GTP Binding Protein Regulators, Regulators, GTP-Binding Protein, Regulating Factors, G-Protein, G-Protein Regulating Factors, 0, Regulating Factors, GTP Binding Protein, G Protein Signaling Regulators, Regulators, G-Protein Signaling, Signaling Regulators, G-Protein, GTP-Binding Protein Regulators, G-Protein Signaling Regulators