Phosphotransferases that catalyzes the conversion of 1-phosphatidylinositol to 1-phosphatidylinositol 3-phosphate. Many members of this enzyme class are involved in RECEPTOR MEDIATED SIGNAL TRANSDUCTION and regulation of vesicular transport with the cell. Phosphatidylinositol 3-Kinases have been classified both according to their substrate specificity and their mode of action within the cell.

Synonyms: Kinases, Phosphoinositide 3, Phosphatidylinositol 3 OH Kinase, 3-Hydroxykinase, Phosphoinositide, PI-3K, Phosphoinositide 3 Kinases, PI 3-Kinase, PI3 Kinases, PI 3 Kinase, Phosphoinositide 3 Hydroxykinase, Phosphatidylinositol-3-OH Kinase, Phosphatidylinositol 3 Kinases, PtdIns 3-Kinase, Phosphatidylinositol 3-Kinases, PI-3 Kinase, PtdIns 3 Kinase, PtdIns 3 Kinases, EC 2.7.1.-, PI3-Kinase, PtdIns 3-Kinases, PI3 Kinase, Kinase, Phosphatidylinositol-3-OH, Kinase, PI-3, Phosphoinositide 3-Hydroxykinase, Kinases, PI3