A serine protease that catalyses the release of an N-terminal dipeptide. Several biologically-active peptides have been identified as dipeptidyl peptidase 4 substrates including INCRETINS; NEUROPEPTIDES; and CHEMOKINES. The protein is also found bound to ADENOSINE DEAMINASE on the T-CELL surface and is believed to play a role in T-cell activation.
Synonyms: EC 3.4.14.5, Dipeptidyl Peptidase IV, Dipeptidyl-Peptidase IV, CD26 Antigens, Antigens, CD26, Adenosine Deaminase Complexing Protein 2, Dipeptidyl Peptidase 4, Antigen, CD26, CD26 Antigen
Instance information
2011(1998) ,2011; see CD26 ANTIGEN 1995-2010; CD26 ANTIGEN was indexed under ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE 1990-1994; DIPEPTIDYL PEPTIDASE IV was indexed under DIPEPTIDYL PEPTIDASES 1980-1994
D018819