Regulatory sequences important for viral replication that are located on each end of the HIV genome. The LTR includes the HIV ENHANCER, promoter, and other sequences. Specific regions in the LTR include the negative regulatory element (NRE), NF-kappa B binding sites , Sp1 binding sites, TATA BOX, and trans-acting responsive element (TAR). The binding of both cellular and viral proteins to these regions regulates HIV transcription.

Synonyms: HIV Trans Acting Responsive Region, Negative Regulatory Element, HIV, HIV Long Terminal Repeat, TAR Element, HIV, Long Terminal Repeat, HIV, HIV Sp1-Binding Site, Trans Activation Responsive Element, HIV, Human Immunodeficiency Virus Long Terminal Repeat, Trans Acting Responsive Region, HIV, HIV Sp1 Binding Site, HIV TAR Elements, LTR, Human Immunodeficiency Virus, HIV-1 LTR, HIV 1 LTR, HIV TAR Element, Sp1-Binding Sites, HIV, Trans-Activation Responsive Element, HIV, HIV Trans-Acting Responsive Region, Trans Activation Responsive Region, HIV, Sp1-Binding Site, HIV, Trans-Activation Responsive Region, HIV, Sp1 Binding Site, HIV, LTR, HIV-1, HIV Negative Regulatory Element, TAR Elements, HIV, Trans-Acting Responsive Region, HIV, HIV Sp1-Binding Sites, Human Immunodeficiency Virus LTR