2-Substituted benzimidazole first introduced in 1962. It is active against a variety of nematodes and is the drug of choice for STRONGYLOIDIASIS. It has CENTRAL NERVOUS SYSTEM side effects and hepatototoxic potential. (From Smith and Reynard, Textbook of Pharmacology, 1992, p919)

Synonyms: 0, Thibendole, N1Q45E87DT, Mintezol, 2-(4'-Thiazolyl)Benzimidazole, 1H-Benzimidazole, 2-(4-thiazolyl)-, Mintesol, Omnizole, Tiabendazol, Thiabendazole