A specialized subpopulation of CD4+ T cells involved in formation of GERMINAL CENTER. Tfh cells are mostly located in secondary lymphoid organs, e.g., TONSIL; SPLEEN and LYMPH NODES. They are CD4 ANTIGEN; CD45 ANTIGEN; B-CELL LYMPHOMA 6 PROTEIN; CXCR5 RECEPTORS; ICOS INDUCIBLE T-CELL CO-STIMULATOR; and PD1 RECEPTOR positive.

Synonyms: Follicular B Helper T Cells, T Follicular Helper Cells, Tfh Cell, Tfh Cells, Follicular Helper T Cells