Mitochondrial Permeability Transition Pore

Mitochondrial Permeability Transition Pore

http://id.nlm.nih.gov/mesh/D000083162

A multiprotein inner mitochondrial complex which opens only under certain pathological conditions (e.g., OXIDATIVE STRESS) uncoupling the membrane leading to APOPTOSIS and MITOCHONDRIAL TRANSMEMBRANE PERMEABILITY-DRIVEN NECROSIS particularly in CARDIOMYOCYTES during MYOCARDIAL REPERFUSION INJURY.

Synonyms: Mitochondrial Permeability Transition Pore (mPTP), 0, Mitochondrial Permeability Transition Pore, mPTP Protein, Mitochondrial Megachannel

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Mitochondrial Permeability Transition Pore was indexed under MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS 2007-2020; ION CHANNELS 2003-2006; MEMBRANE PROTEINS 1999-2002; CYCLOSPORINS 1999-2000 ,2021(1999)

identifier

D000083162

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Mitochondrial Permeability Transition Pore