A Poly(A) RNA-binding protein that negatively regulates EGFR ENDOCYTOSIS. An increased risk for developing AMYOTROPHIC LATERAL SCLEROSIS 13 is observed in patients who have more than 23 CAG repeats in the ATXN2 gene coding sequence. Larger CAG expansions in the ATXN2 gene occur in SPINOCEREBELLAR ATAXIA 2 patients.

Synonyms: Protein, Atx-2, Ataxin-2, Spinocerebellar Ataxia Type 2 Protein, Atx 2 Protein, SCA2 Protein, Ataxin 2 Protein, 0, Ataxin 2, ATXN2 Protein, Ataxin-2 Protein, Protein, Ataxin-2, Protein, ATXN2, Atx-2 Protein, Protein, SCA2

Instance information

comment

2016; use SCA2 PROTEIN (NM) 1996-2015 ,2016; ATAXIN-2 was indexed under PROTEINS 1996-2005, and under NERVE TISSUE PROTEINS 2005-2015

identifier

D000067698

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