A family of predominantly nuclear proteins that regulate gene transcription and protein degradation. The expansion of CAG trinucleotide repeats in genes that encode Ataxins is associated with SPINOCEREBELLAR ATAXIAS (SCA). In SCA patients, the number of CAG repeats correlates with the severity of disease and inversely correlates with the age of disease onset.

Synonyms: Proteins, Spinocerebellar Ataxia, Spinocerebellar Ataxia Proteins, Ataxia Protein, Spinocerebellar, Spinocerebellar Ataxia Protein, Proteins, Ataxin, Ataxin Proteins, 0, Ataxins, Ataxin, Protein, Spinocerebellar Ataxia, Protein, Ataxin, Ataxia Proteins, Spinocerebellar, Ataxin Protein